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4D Molecular Therapeutics

FDMT
33
Biotechnology · Healthcare
Exchange
NASDAQ
Winston Score
33
Winston is serious
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Mixed
Cash Flow
Weak
Stability
Good
Valuation
Data not available

Winston Score History

The full picture

4D Molecular Therapeutics is a clinical-stage biotech company that develops gene therapies — treatments that deliver working copies of genes directly into a patient's cells to fix diseases caused by faulty genes. Its main focus is on serious eye diseases, lung conditions, and heart diseases. The company has built a library of engineered proteins called "vectors" that carry genetic material into the body, which it calls its Therapeutic Vector Evolution platform.

The company does not yet sell any approved products, so it earns money primarily through research partnerships and licensing deals with larger pharmaceutical companies rather than product sales. It operates mainly in the United States and is considered a small-cap company with a market cap around $500 million. Its proprietary vector library gives it a potential edge over competitors, but like most clinical-stage biotechs, its biggest risk is that its drug candidates could fail in clinical trials, which would significantly pressure its cash runway and ability to continue operations.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

>+1,000% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

-6.1% YoY

YoY Growth Rate

Earnings declining

Insider Activity

25.4%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~15 months

$361M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Strong grower

4D Molecular Therapeutics is growing revenue at 25107% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-2037.2%
Losing money on operations — -2037.2%
Return on the money invested
ROCE
-46.1%
Weak — -46.1% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
>+1,000%
Fast-growing sales (>+1,000% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
1/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-170.5%
Burning cash (-170.5%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.05
Conservative — low debt load (0.05)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
no trend
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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