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Akebia Therapeutics

AKBA
27
Biotechnology · Healthcare
Price
$0.91
-0.01 (-1.39%)
Market Cap
$243.2M
Exchange
NASDAQ
Winston Score
27
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Mixed
Cash Flow
Weak
Stability
Weak
Valuation
Data not available

Share count rising — dilution

+55.0% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 165.9M (2021) → 257.2M (2025)

Winston Score History

The full picture

Akebia Therapeutics is a biopharmaceutical company focused on treating anemia caused by chronic kidney disease (CKD). Its main product is Vafseo (vadadustat), an oral pill that helps the body produce more red blood cells. The drug targets patients on dialysis and those with CKD who are not yet on dialysis, competing against injectable treatments that have dominated this market for decades.

Akebia earns revenue primarily through product sales of Vafseo in the United States, where it received FDA approval in 2024, as well as through licensing and collaboration agreements with partners in other regions. The company is small, with a market cap around $400 million, and its main competitive edge is offering an oral alternative to injectable anemia drugs made by much larger rivals. The key growth driver is expanding Vafseo's commercial uptake among nephrologists and dialysis centers, while the main risk is that gaining market share against entrenched injectable therapies with established reimbursement and prescribing habits will be difficult and slow.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-21.4% YoY

YoY Growth Rate

Revenue declining

EPS Growth

<−1,000% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$62M/ year

Rising (+66% vs prior year)

26.4% of revenue

In line with sector average (18%)

Investing heavily in future products and technology

Insider Activity

2.3%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~2 years

$156M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$156M cash & investments at current burn rate

Heavy R&D investment

Akebia Therapeutics is putting 26% of revenue into R&D and that number is rising. With 2+ years of cash runway, they have time to let it pay off.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
78.8%
Premium pricing power — 78.8% gross margin
Profit after running costs
Operating Margin
-12.9%
Losing money on operations — -12.9%
Return on the money invested
ROCE
-20.3%
Weak — -20.3% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+7.5%
Steady sales growth (+7.5% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
4/8 quarters
Earnings inconsistent quarter-to-quarter

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
8.6%
Modest free cash flow (8.6%)

FCF margin between 0% and 10%. Some cash from sales, but not a lot.

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Stability

What it owes vs what it owns
Debt / Equity
1.98
Elevated debt (1.98)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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