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Arcus Biosciences

RCUS
29
Biotechnology · Healthcare
Price
$30.34
+0.82 (+2.78%)
Market Cap
$3.82B
Winston Score
29
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Weak
Cash Flow
Weak
Stability
Good
Valuation
Data not available

Share count rising — dilution

+45.2% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 74.0M (2021) → 107.4M (2025)

Winston Score History

The full picture

Arcus Biosciences is a clinical-stage biotechnology company focused on developing cancer treatments. It creates small-molecule and antibody drugs that work by blocking signals cancer cells use to hide from the immune system. Its main customers are patients with solid tumors, and its drugs are tested in partnership with major pharmaceutical companies, most notably Gilead Sciences.

Arcus earns money primarily through collaboration agreements and milestone payments from partners like Gilead, rather than product sales, since none of its drugs have received full regulatory approval yet. The company operates mainly in the United States and is still in the money-losing phase typical of early-stage biotech, spending heavily on clinical trials. Its key growth driver is the potential approval of its lead drug candidate, domvanalimab, an anti-TIGIT antibody — but the main risk is clinical failure, as many cancer immunotherapy drugs have struggled to prove meaningful benefit in late-stage trials.

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Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-74.4% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-800.0% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$523M/ year

Rising (+17% vs prior year)

211.7% of revenue

11.8x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

29.3%ownership

Rising

Insiders increasing their stake — aligned with shareholders

Cash Runway

~18 months

$702M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Heavy R&D investment

Arcus Biosciences is putting 212% of revenue into R&D and that number is rising. That's 11.8x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-234.1%
Losing money on operations — -234.1%
Return on the money invested
ROCE
-86.0%
Weak — -86.0% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
-55.3%
Shrinking sales (-55.3% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
4/8 quarters
Earnings inconsistent quarter-to-quarter

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-406.0%
Burning cash (-406.0%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.22
Conservative — low debt load (0.22)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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