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Ardelyx

ARDX
23
Biotechnology · Healthcare
Exchange
NASDAQ
Winston Score
23
Winston is worried
Weak fundamentals across most pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Mixed
Cash Flow
Weak
Stability
Weak
Valuation
Data not available

Winston Score History

The full picture

Ardelyx is a small biotechnology company that makes medicines for people with kidney disease and related conditions. Its main approved drug is Xphozah (tenapanor), which helps control high phosphorus levels in adults on dialysis — a serious problem that can damage the heart and bones. It also sells Ibsrela, a treatment for irritable bowel syndrome with constipation.

Ardelyx earns money by selling these prescription drugs directly to patients and healthcare providers in the United States. The company is relatively small, with a market cap around $1.2 billion, and its high gross margin of roughly 92% reflects the typical economics of a commercial-stage drug company once manufacturing costs are covered. However, Ardelyx is still spending more than it earns overall, as shown by its negative operating margin, meaning it is not yet consistently profitable. The key growth driver is expanding Xphozah's adoption among the large dialysis patient population, while the main risk is competition from established phosphate binders and potential pricing pressure from insurers.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+23.8% YoY

YoY Growth Rate

Steady revenue growth

EPS Growth

+11.9% YoY

YoY Growth Rate

Steady EPS growth

Insider Activity

4.0%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~22 months

$282M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Growth context

Ardelyx is growing revenue at 24% year-over-year. The Winston Score measures business quality today — these growth metrics show what could matter tomorrow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Profit per sale
Gross Margin
95.2%
Premium pricing power — 95.2% gross margin
Profit after running costs
Operating Margin
-10.3%
Losing money on operations — -10.3%
Return on the money invested
ROCE
-8.8%
Weak — -8.8% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+16.8%
Fast-growing sales (+16.8% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
3/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-11.1%
Burning cash (-11.1%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
1.69
Elevated debt (1.69)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
no trend
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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