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Assembly Biosciences

ASMB
43
Biotechnology · Healthcare
Price
$34.38
+0.85 (+2.54%)
Market Cap
$681.3M
Exchange
NASDAQ
Winston Score
43
Winston is serious
Mixed quality — meaningful strengths and weaknesses.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Strong
Cash Flow
Weak
Stability
Good
Valuation
Weak

Share count rising — dilution

+210.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 3.6M (2021) → 11.2M (2025)

Winston Score History

The full picture

Assembly Biosciences is a small biotechnology company focused on developing antiviral drugs. It works on treatments for serious viral infections, with its main research targeting hepatitis B virus (HBV) — a liver disease that affects hundreds of millions of people worldwide. The company does not yet sell approved products; it is in the clinical-stage, meaning its drugs are still being tested in human trials.

Assembly makes almost no revenue from product sales yet. It funds its operations through partnerships with larger pharmaceutical companies and by raising money from investors. It operates primarily in the United States, though its clinical trials involve patients globally. The company's potential edge lies in its pipeline of novel antiviral compounds that work differently from existing hepatitis B treatments, but the biggest risk is that drug development is expensive and uncertain — if its clinical trials fail or funding runs out, the company could face serious financial pressure.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+38.9% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

+85.0% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$65M/ year

Rising (+16% vs prior year)

89.6% of revenue

5.0x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

45.9%ownership

Rising

Insiders increasing their stake — aligned with shareholders

Cash Runway

~5 years

$320M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$320M cash & investments at current burn rate

Strong grower

Assembly Biosciences is growing revenue at 39% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-47.4%
Losing money on operations — -47.4%
Return on the money invested
ROCE
-2.9%
Weak — -2.9% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+125.1%
Fast-growing sales (+125.1% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
8/8 quarters
Every recent quarter grew earnings vs last year

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-51.5%
Burning cash (-51.5%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.01
Conservative — low debt load (0.01)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
62.5x
Expensive — P/E 62.5

P/E over 35. The market is pricing in heavy, sustained growth.

Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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