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Deep Value: cash covers more than 100% of the stock price

This company holds roughly $57M in cash and investments — more than its entire stock-market value, based on its latest quarterly filing. You're paying very little for the actual business. Sometimes that's a genuine bargain or a takeover target, sometimes it's cheap for a reason. Not a buy signal on its own — always ask why it's this cheap.

aTyr Pharma logo

aTyr Pharma

ATYR
8
Biotechnology · Healthcare
Price
$0.50
-0.00 (-0.30%)
Market Cap
$49.2M
Exchange
NASDAQ
Winston Score
8
Winston is worried
Weak fundamentals across most pillars.
Based on the IPO prospectus (annual filing). This score will refine automatically once the company reports its first quarters.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Weak
Growth
Weak
Cash Flow
Weak
Stability
Good
Valuation
Data not available

Share count rising — dilution

+387.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 19.1M (2021) → 93.0M (2025)

Winston Score History

The full picture

aTyr Pharma is a small biotechnology company focused on discovering and developing medicines for rare diseases. Its main work centers on a class of proteins called aminoacyl-tRNA synthetases, which the company believes can be turned into drugs that calm overactive immune responses. Its lead drug candidate, efzofitimod, is being tested in patients with a rare lung disease called pulmonary sarcoidosis.

The company earns almost no revenue today and funds its operations primarily through stock offerings and partnerships, which is typical for early-stage biotech firms. aTyr is based in San Diego, California, and operates entirely in the United States at this stage of development. The deeply negative margins reflect the reality that it is spending heavily on clinical trials without yet selling an approved product. The biggest risk the company faces is whether efzofitimod will succeed in late-stage clinical trials, since a failed trial would severely threaten its ability to continue operating.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

YoY Growth Rate

Revenue data limited

EPS Growth

+50.0% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$60M/ year

Rising (+11% vs prior year)

>1,000% of revenue

1760.8x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

2.6%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~5 months

$16M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Heavy R&D investment

aTyr Pharma is putting 31694% of revenue into R&D and that number is rising. That's 1760.8x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
-717.4%
Thin — -717.4% gross margin
Profit after running costs
Operating Margin
-40856.3%
Losing money on operations — -40856.3%
Return on the money invested
ROCE
-112.6%
Weak — -112.6% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
-19.1%
Shrinking sales (-19.1% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
N/A
Data not available

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-32664.7%
Burning cash (-32664.7%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.02
Conservative — low debt load (0.02)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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