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Crescent Biopharma

CBIO
Biotechnology · Healthcare
Price
$17.15
+0.92 (+5.67%)
Market Cap
$637.0M
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+1923.9% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 515K (2021) → 10.4M (2025)

Winston Score History

The full picture

Crescent Biopharma is a small biotechnology company focused on developing cancer treatments. It works on drugs that help the immune system fight tumors, a field called oncology. The company does not yet sell approved products and is still in the early stages of clinical research.

Crescent Biopharma makes no meaningful revenue today, which explains its deeply negative operating margin. It funds operations through equity raises and relies entirely on future drug approvals to generate sales. The company operates primarily in the United States and competes in a crowded oncology drug development space against much larger pharmaceutical companies with more resources. The central risk is straightforward: if its drug candidates fail in clinical trials or cannot win regulatory approval, the company may struggle to survive without raising additional capital, which can dilute existing shareholders.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

<−1,000% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$138M/ year

Rising (+392% vs prior year)

>1,000% of revenue

70.7x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

22.7%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~2 years

$172M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$172M cash & investments at current burn rate

Heavy R&D investment

Crescent Biopharma is putting 1273% of revenue into R&D and that number is rising. That's 70.7x the sector average. With 2+ years of cash runway, they have time to let it pay off.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-102.3%
Weak — -102.3% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
1/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-1225.4%
Burning cash (-1225.4%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.01
Conservative — low debt load (0.01)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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