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Cue Biopharma

CUE
27
Biotechnology · Healthcare
Price
$23.98
-0.63 (-2.56%)
Market Cap
$63.0M
Exchange
NASDAQ
Winston Score
27
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Strong
Cash Flow
Weak
Stability
Data not available
Valuation
Data not available

Share count rising — dilution

+202.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 1.0M (2021) → 3.2M (2025)

Winston Score History

The full picture

Cue Biopharma is a small biotech company focused on developing drugs that train the immune system to fight cancer. Its core approach uses engineered proteins called "Immuno-STATs" that are designed to selectively activate certain immune cells without triggering harmful side effects seen with older cancer treatments. The company's main customers would be patients and healthcare providers, and it operates in the competitive oncology drug development space.

Cue Biopharma makes almost no product revenue yet — it earns money primarily through research collaborations and grants while spending heavily to advance its drug candidates through clinical trials. The company is based in the United States and, with a market cap of roughly $100 million, is considered a micro-cap biotech. Its near-100% gross margin reflects the early-stage nature of its limited revenue, but its deeply negative operating margin shows it is burning cash. The central risk is whether its pipeline candidates will succeed in clinical trials, since failure there would severely threaten the company's ability to survive without raising additional capital.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+166.7% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

-806.2% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$38M/ year

Flat (+4% vs prior year)

137.4% of revenue

7.6x the sector average (18%)

Steady R&D investment year-over-year

Insider Activity

0.8%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~2 months

$17M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

Short runway — potential dilution ahead through share issuance

Strong grower

Cue Biopharma is growing revenue at 167% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
99.5%
Premium pricing power — 99.5% gross margin
Profit after running costs
Operating Margin
-1113.3%
Losing money on operations — -1113.3%
Return on the money invested
ROCE
-4270.3%
Weak — -4270.3% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+354.4%
Fast-growing sales (+354.4% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
7/8 quarters
Every recent quarter grew earnings vs last year

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-133.2%
Burning cash (-133.2%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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