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Definium Therapeutics

DFTX
Biotechnology · Healthcare
Price
$44.91
-0.49 (-1.08%)
Market Cap
$5.96B
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+226.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 27.4M (2021) → 89.3M (2025)

Winston Score History

The full picture

Definium Therapeutics is a clinical-stage biotechnology company focused on developing new medicines to treat serious diseases. Like most early-stage biotechs, it does not yet sell approved products to patients — instead, it runs clinical trials to test whether its experimental drug candidates are safe and effective. Its main customers, if its drugs succeed, would be patients and healthcare systems in need of treatments for conditions the company is targeting.

Definium generates no product revenue yet, which explains its 0% gross margin and negative returns on capital. It funds operations primarily through equity raises, partnerships, or licensing deals with larger pharmaceutical companies. The company likely operates mainly in the United States, as is typical for firms of its size and stage. The key risk is straightforward: clinical trials frequently fail, and if its lead drug candidates do not show strong results in trials, the company could face significant cash burn without a clear path to revenue.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

-188.0% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$118M/ year

Rising (+80% vs prior year)

R&D investment increasing — building for the future

Insider Activity

2.9%ownership

Relatively low insider ownership

Cash Runway

~3 years

$1.1B cash & investments

$1.1B cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-24.8%
Weak — -24.8% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
3/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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