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Dyadic International

DYAI
20
Biotechnology · Healthcare
Price
$0.69
-0.01 (-1.43%)
Market Cap
$25.1M
Exchange
NASDAQ Capital Market
Winston Score
20
Winston is worried
Weak fundamentals across most pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Weak
Growth
Mixed
Cash Flow
Weak
Stability
Data not available
Valuation
Data not available

Share count rising — dilution

+17.2% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 27.8M (2021) → 32.6M (2025)

Winston Score History

The full picture

Dyadic International is a small biotechnology company that develops technology to help make medicines faster and cheaper. Its main product is a platform called C1, which uses a fungus to produce large amounts of proteins — the building blocks used in vaccines, antibodies, and other biological drugs. The company licenses this technology to pharmaceutical and biotech companies that want a more efficient way to manufacture their medicines.

Dyadic earns money primarily through research collaborations, licensing agreements, and grants rather than selling finished drugs itself. It operates mainly in the United States but partners with organizations around the world, including research institutions and drug developers. The company is very small, with a market cap near zero and deep operating losses, meaning it spends far more than it earns. The key growth driver is whether larger pharmaceutical partners adopt the C1 platform at scale, but the main risk is that the company may run out of funding before that happens.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+107.4% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

-0.7% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$2M/ year

Rising (+5% vs prior year)

174.8% of revenue

9.7x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

25.3%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~5 months

$3M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Strong grower

Dyadic International is growing revenue at 107% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
-2.4%
Thin — -2.4% gross margin
Profit after running costs
Operating Margin
-213.7%
Losing money on operations — -213.7%
Return on the money invested
ROCE
-77.4%
Weak — -77.4% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+1.5%
Nearly flat sales (+1.5% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
6/8 quarters
Earnings grew in most of the last 8 quarters

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-213.2%
Burning cash (-213.2%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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