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enGene Holdings

ENGN
Biotechnology · Healthcare
Price
$1.78
+0.01 (+0.56%)
Market Cap
$119.2M
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+223.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 15.8M (2021) → 51.1M (2025)

Winston Score History

The full picture

enGene Holdings is a small biotechnology company focused on developing gene therapy treatments for bladder cancer. It uses a technology platform called D-Linux to deliver genetic material directly into cells lining the bladder, without needing to alter the patient's DNA permanently. The company's main customers would be cancer patients and the hospitals or clinics that treat them.

enGene makes no revenue yet, which is typical for early-stage biotech companies that are still running clinical trials. It operates primarily in North America and is a very small company with a market cap around $100 million. Its main competitive edge is its proprietary D-Linux delivery platform, which it claims can target bladder tissue more precisely than older methods. The biggest risk the company faces is clinical and financial — it must prove its treatments work in trials while continuing to spend cash it does not yet earn back, meaning it may need to raise more money from investors to survive.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

+184.3% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$94M/ year

Rising (+147% vs prior year)

R&D investment increasing — building for the future

Insider Activity

63.4%ownership

Rising

Insiders increasing their stake — aligned with shareholders

Cash Runway

~2 years

$285M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$285M cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-24.3%
Weak — -24.3% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
3/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
0.11
Conservative — low debt load (0.11)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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