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hVIVO

HVO.L
15
Biotechnology · Healthcare
Price
6.55 GBp
-0.05 (-0.76%)
Market Cap
45.1M GBp
Exchange
London Stock Exchange
Winston Score
15
Winston is worried
Weak fundamentals across most pillars.
Data as of Aug 23, 2026 · filings through Dec 31, 2025
How the score breaks down
Quality
Weak
Growth
Weak
Cash Flow
Weak
Stability
Data not available
Valuation
Data not available

Share count rising — dilution

+2.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 670.2M (2021) → 685.7M (2025)

Winston Score History

The full picture

hVIVO is a UK-based contract research company that helps pharmaceutical and biotech firms test new medicines and vaccines. It does this using a special method called "human challenge trials," where healthy volunteers are deliberately exposed to viruses like the flu or common cold in a controlled clinic setting. This lets drug companies see quickly whether their treatments actually work, without running large, expensive trials in the general public.

hVIVO earns money by charging clients — mostly large pharmaceutical companies and biotech firms — fees to run these studies at its dedicated quarantine clinic in London. The company operates primarily in the UK but serves clients globally. Its main competitive advantage is its specialized expertise and infrastructure for human challenge trials, which are difficult to replicate and subject to strict regulatory oversight. The key growth driver is rising demand for faster, cheaper drug development, but the company currently operates at a loss, and its small size makes it vulnerable to project delays or client cancellations.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-11.6% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-206.2% YoY

YoY Growth Rate

Earnings declining

R&D Spend

£-6M/ year

-12.3% of revenue

Below sector average (18%)

Research and development spending

Insider Activity

17.0%ownership

Insiders own a meaningful stake in the company

Cash Runway

~6 months

£14M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Short runway — potential dilution ahead through share issuance

Cash watch

hVIVO has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
-26.3%
Thin — -26.3% gross margin
Profit after running costs
Operating Margin
-26.3%
Losing money on operations — -26.3%
Return on the money invested
ROCE
-16.5%
Weak — -16.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
-23.4%
Shrinking sales (-23.4% YoY)
Profit growth
EPS YoY
-156.1%
Earnings shrinking (-156.1% YoY)

Earnings per share down more than 10%. Either a bad year, or a real decline.

How steady the profit is
EPS Consistency
4/8 quarters
Earnings inconsistent quarter-to-quarter

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-32.3%
Burning cash (-32.3%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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