Kyverna Therapeutics

KYTX

Biotechnology · Healthcare

Exchange

NASDAQ

Winston Score

–

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Winston Score History

The full picture

Kyverna Therapeutics is a clinical-stage biotechnology company focused on developing cell therapies for autoimmune diseases. Its lead approach uses engineered CAR-T cells — immune cells reprogrammed in a lab — to target and reset the immune system in patients with conditions like lupus, multiple sclerosis, and myasthenia gravis. The company's main customers are patients with serious autoimmune diseases that have not responded well to existing treatments.

Kyverna does not yet generate product revenue, as its therapies are still in clinical trials. It is based in the United States and funds its operations through equity raises and partnerships rather than product sales, which is typical for early-stage biotech companies. The company's negative ROIC reflects heavy spending on research and trials with no approved products yet. The key risk is whether its lead therapy, KYV-101, can demonstrate strong enough safety and effectiveness data to win regulatory approval and eventually reach patients.

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

+35.1% YoY

YoY Growth Rate

EPS growth accelerating

Insider Activity

54.7%ownership

→ Flat

Insider ownership roughly steady over the past year

Cash Runway

~15 months

$199M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale

Gross Margin

N/A

—

Data not available

Profit after running costs

Operating Margin

N/A

—

Data not available

Return on the money invested

ROCE

-83.5%

Weak — -83.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth

Sales YoY

N/A

—

Data not available

Profit growth

EPS YoY

N/A

—

Data not available

How steady the profit is

EPS Consistency

4/8 quarters

Earnings inconsistent quarter-to-quarter

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Cash Flow

Profit that turns into cash

Cash Conversion

N/A

—

Data not available

Spare cash per sale

FCF Margin

N/A

—

Data not available

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Stability

What it owes vs what it owns

Debt / Equity

0.15

Conservative — low debt load (0.15)

Covers its interest

Interest Cover

N/A

Data not available

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Valuation

Price vs profit

P/E Ratio (TTM)

N/M

no trend

Negative earnings — P/E not meaningful

Cheaper or dearer next year

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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