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Palisade Bio

PALI
Biotechnology · Healthcare
Price
$2.10
+0.04 (+1.94%)
Market Cap
$364.5M
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+446580.7% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 12K (2021) → 55.7M (2025)

Winston Score History

The full picture

Palisade Bio is a small biotechnology company focused on developing drugs to treat serious gastrointestinal conditions. Its lead program targets intestinal barrier dysfunction — a problem where the gut lining becomes "leaky," allowing harmful substances into the bloodstream. The company's main customers would be patients and hospitals dealing with conditions like post-surgical complications and inflammatory bowel disease.

Palisade Bio does not yet sell any approved products, so it currently earns no revenue. It funds its operations through equity offerings and other financing, which is typical for early-stage biotech companies. The company operates primarily in the United States and has a small market capitalization of roughly $400 million. Its competitive position depends entirely on clinical trial success — if its lead drug candidate fails in trials or cannot win FDA approval, the company faces significant financial pressure since it has no other revenue stream to fall back on.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

+91.4% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$10M/ year

Rising (+12% vs prior year)

R&D investment increasing — building for the future

Insider Activity

3.8%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~4 years

$125M cash & investments

$125M cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-2339.6%
Losing money on operations — -2339.6%
Return on the money invested
ROCE
-29.0%
Weak — -29.0% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
7/8 quarters
Every recent quarter grew earnings vs last year

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-3638.0%
Burning cash (-3638.0%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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