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Praxis Precision Medicines

PRAX
Biotechnology · Healthcare
Price
$375.94
+11.36 (+3.12%)
Market Cap
$10.48B
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+695.1% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 2.8M (2021) → 22.5M (2025)

Winston Score History

The full picture

Praxis Precision Medicine is a clinical-stage biotechnology company focused on developing drugs for brain disorders caused by genetic mutations. Its main targets are epilepsy and essential tremor — conditions where abnormal electrical activity in the brain causes seizures or uncontrollable shaking. The company's lead drug candidates, including ulixacaltamide and elsunersen, are designed to treat specific genetic forms of these diseases, meaning they are aimed at patients whose conditions are caused by identifiable gene variants.

Praxis does not yet sell any approved products, so it currently earns no revenue — a typical situation for clinical-stage biotechs. The company is based in Cambridge, Massachusetts, and funds its operations through equity raises and partnerships rather than product sales, which explains its negative returns on capital. Its potential competitive edge lies in targeting precise genetic subtypes of neurological disease, which could allow for more effective treatments than older, broader drugs. The main risk is that its drug candidates could fail in late-stage clinical trials, which would significantly impact the company's future.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

YoY Growth Rate

Revenue data limited

EPS Growth

+13.3% YoY

YoY Growth Rate

Steady EPS growth

R&D Spend

$267M/ year

Rising (+75% vs prior year)

R&D investment increasing — building for the future

Insider Activity

6.3%ownership

Rising

Insiders increasing their stake — aligned with shareholders

Cash Runway

~2 years

$759M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$759M cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-28.2%
Weak — -28.2% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
-100.0%
Shrinking sales (-100.0% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
3/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
0.00
Conservative — low debt load (0.00)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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