WinstonWınston
Back
PYC Therapeutics Limited logo

PYC Therapeutics Limited

PYC.AX
21
Biotechnology · Healthcare
Price
A$2.07
-0.13 (-5.91%)
Market Cap
A$1.21B
Exchange
Australian Securities Exchange
Winston Score
21
Winston is worried
Weak fundamentals across most pillars.
Based on the IPO prospectus (annual filing). This score will refine automatically once the company reports its first quarters.
Data as of Aug 23, 2026 · filings through Dec 31, 2025
How the score breaks down
Quality
Mixed
Growth
Weak
Cash Flow
Weak
Stability
Good
Valuation
Data not available

Share count falling — buybacks

84.0% over 4y

The company has reduced its share count over this period, returning value to shareholders through buybacks.

Diluted shares outstanding: 3.13B (2021) → 500.5M (2025)

Winston Score History

The full picture

PYC Therapeutics is an Australian biotechnology company that develops RNA-based medicines to treat rare genetic diseases. Its lead program targets VP-001, a treatment for retinitis pigmentosa, a rare inherited condition that causes progressive blindness. The company focuses on patients with few or no existing treatment options, which is a common strategy among rare disease drug developers.

PYC does not yet sell any approved products, so it generates almost no revenue — its high gross margin reflects minimal cost of goods on small research grants or licensing income rather than commercial sales. The company is based in Perth, Australia, and funds its operations through capital raises and partnerships rather than product revenue. Its main competitive edge lies in its proprietary cell-penetrating peptide technology, which is designed to deliver RNA therapies directly into target cells. The central risk is that the company must successfully advance its drug candidates through clinical trials and secure regulatory approval before it can generate meaningful commercial revenue.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-100.0% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-487.7% YoY

YoY Growth Rate

Earnings declining

R&D Spend

A$70M/ year

Rising (+24% vs prior year)

298.2% of revenue

16.6x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

64.3%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~12 months

A$121M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Heavy R&D investment

PYC Therapeutics Limited is putting 298% of revenue into R&D and that number is rising. That's 16.6x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-228.3%
Losing money on operations — -228.3%
Return on the money invested
ROCE
-31.6%
Weak — -31.6% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

Full breakdown available with your free trial

See every metric, trend, and what it means for this stock.

Try free

Growth

Sales growth
Sales YoY
+6.5%
Slow sales growth (+6.5% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
N/A
Data not available

Full breakdown available with your free trial

See every metric, trend, and what it means for this stock.

Try free

Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-223.6%
Burning cash (-223.6%)

Free cash flow is negative. They are burning cash, not generating it.

Full breakdown available with your free trial

See every metric, trend, and what it means for this stock.

Try free

Stability

What it owes vs what it owns
Debt / Equity
0.00
Conservative — low debt load (0.00)
Covers its interest
Interest Cover
N/A
Data not available

Full breakdown available with your free trial

See every metric, trend, and what it means for this stock.

Try free

Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

Full breakdown available with your free trial

See every metric, trend, and what it means for this stock.

Try free

Dividends

Not applicable for this business.
🔒 See full fundamentals and if they are improving or declining — click here for your free trial now.
Start free trial