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Sarepta Therapeutics

SRPT
28
Biotechnology · Healthcare
Also trades as: 0L35.L
Exchange
NASDAQ
Winston Score
28
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Mixed
Growth
Weak
Cash Flow
Weak
Stability
Mixed
Valuation
Data not available

Winston Score History

The full picture

Sarepta Therapeutics is a biotech company that makes medicines for rare genetic muscle diseases, mainly Duchenne muscular dystrophy (DMD). DMD is a severe condition that affects mostly young boys, causing progressive muscle weakness. Sarepta's main products include exon-skipping drugs like Exondys 51, Vyondys 53, and Amondys 45, as well as Elevidys, a gene therapy for DMD approved by the FDA in 2023.

Sarepta earns money by selling these prescription drugs to patients, primarily in the United States, though it is expanding internationally through partnerships. With a market cap of about $1.7 billion and a gross margin above 60%, the company has pricing power in a niche where few competitors exist. However, its operating margin is slightly negative, meaning it still spends heavily on research. The biggest growth driver is broader adoption of Elevidys, its gene therapy, but the main risk is that insurers may limit coverage due to the drug's very high price tag.

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Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-34.3% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-102.5% YoY

YoY Growth Rate

Earnings declining

Insider Activity

10.4%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

5+ years

Quarterly Free Cash Flow

→ Burn rate stable

$934M cash & investments at current burn rate

Revenue declining

Sarepta Therapeutics's revenue is actually shrinking. In a growth stock, that removes the core investment thesis. The low Winston Score here may be warranted — unless there's a turnaround story.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
62.8%
Premium pricing power — 62.8% gross margin
Profit after running costs
Operating Margin
3.3%
Thin — 3.3% operating margin
Return on the money invested
ROCE
-6.0%
Weak — -6.0% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
-20.4%
Shrinking sales (-20.4% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
4/8 quarters
Earnings inconsistent quarter-to-quarter

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-6.7%
Burning cash (-6.7%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.55
Conservative — low debt load (0.55)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
no trend
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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