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Shuttle Pharmaceuticals Holdings

SHPH
Drug Manufacturers - Specialty & Generic · Healthcare
Price
$3.54
-0.34 (-8.76%)
Market Cap
$2.1M
Exchange
NASDAQ Global Market
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count falling — buybacks

87.9% over 4y

The company has reduced its share count over this period, returning value to shareholders through buybacks.

Diluted shares outstanding: 1.4M (2021) → 164K (2025)

Winston Score History

The full picture

Shuttle Pharmaceuticals is a small clinical-stage drug company focused on developing treatments that make radiation therapy work better against cancer. Its lead product candidate, Ropidoxuridine, is designed to sensitize tumor cells so they are more easily destroyed during radiation treatment. The company targets cancers of the brain, head, neck, and other solid tumors treated with radiotherapy.

Shuttle Pharmaceuticals has no approved products and generates essentially no revenue, funding itself through equity offerings. It is based in the Washington, D.C., area and has a very small market capitalization, making it a micro-cap biotech. The company's potential advantage lies in addressing an unmet need in radiation oncology, but as a pre-revenue firm with significant cash burn and a deeply negative return on capital, its future depends heavily on clinical trial results and its ability to raise additional funding to continue operations.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

+42.7% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$4M/ year

Rising (+12% vs prior year)

R&D investment increasing — building for the future

Insider Activity

0.5%ownership

Relatively low insider ownership

Cash Runway

~1 months

$1M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Short runway — potential dilution ahead through share issuance

Cash watch

Shuttle Pharmaceuticals Holdings has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-334.2%
Weak — -334.2% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
1/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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