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Silexion Therapeutics

SLXN
Biotechnology · Healthcare
Price
$0.34
-0.00 (-0.38%)
Market Cap
$143,967
Exchange
NASDAQ Global Market
Winston Score
Winston looking sleepy
No score yet — nothing to grade.
This is a pre-revenue company — it has no sales yet, just exploration or development costs. There’s no operating business to grade on profitability, margins or cash flow, so the Winston Score stays blank until it starts booking revenue.

Share count rising — dilution

+1108.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 11K (2021) → 133K (2025)

§Winston Score History

The full picture

Silexion Therapeutics is a clinical-stage biotechnology company developing treatments for pancreatic cancer. Its lead drug candidate, called SIL-204 (formerly known as siG12D-LODER), uses RNA interference technology to silence a specific gene mutation that drives tumor growth. The company is focused on one of the hardest-to-treat cancers, where survival rates remain very low.

Because Silexion is still in clinical trials, it does not yet generate product revenue. The company is headquartered in Israel and went public through a merger with a special purpose acquisition company. Its small size means it relies on capital raises to fund operations. The key potential growth driver is positive data from its ongoing clinical trials in pancreatic cancer, but the main risk is significant — most experimental cancer drugs fail in development, and the company faces a long path to potential commercialization with no guarantee of success.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

+88.0% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$7M/ year

Rising (+23% vs prior year)

R&D investment increasing — building for the future

Insider Activity

1.0%ownership

Relatively low insider ownership

Cash Runway

~2 months

$2M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Cash watch

Silexion Therapeutics has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
887.9%
Exceptional — 887.9% return on capital

ROIC above 25%. Every dollar invested in the business earns more than 25 cents back per year.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
7/8 quarters
Every recent quarter grew earnings vs last year

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
22.39
Heavy debt load (22.39)
Covers its interest
Interest Cover
1522.83x
Comfortably covers interest (1522.8x)

Interest coverage above 8. Profits cover interest many times over.

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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