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Sutro Biopharma

STRO
Biotechnology · Healthcare
Price
$21.04
-0.12 (-0.57%)
Market Cap
$203.6M
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+84.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 4.6M (2021) → 8.5M (2025)

Winston Score History

The full picture

Sutro Biopharma is a small biotechnology company that develops experimental cancer drugs. It focuses on a class of medicines called antibody-drug conjugates, or ADCs, which are designed to deliver toxic chemicals directly to cancer cells while leaving healthy cells alone. The company uses its own proprietary cell-free protein synthesis platform, called XpressCF, to build these complex drug molecules in a way that is difficult for competitors to replicate.

Sutro earns money through a mix of research partnerships, licensing deals, and milestone payments from larger pharmaceutical companies, rather than selling approved drugs to patients. It operates primarily in the United States and is still in the clinical-stage, meaning none of its drugs have received regulatory approval yet. The near-98% gross margin on collaboration revenue looks attractive, but the deeply negative operating margin reflects heavy spending on research and clinical trials — the main risk is that the company burns through cash before any drug reaches the market.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-84.6% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-66.4% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$166M/ year

Declining (-34% vs prior year)

162.4% of revenue

9.0x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

29.4%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~13 months

$164M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Revenue declining

Sutro Biopharma's revenue is actually shrinking. In a growth stock, that removes the core investment thesis. The low Winston Score here may be warranted — unless there's a turnaround story.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Profit after running costs
Operating Margin
-303.8%
Losing money on operations — -303.8%
Return on the money invested
ROCE
N/A
Data not available

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Growth

Sales growth
Sales YoY
-56.3%
Shrinking sales (-56.3% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
5/8 quarters
Mixed — about half the quarters showed growth

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-318.6%
Burning cash (-318.6%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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