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Twist Bioscience Corporation

TWST
29
Medical - Diagnostics & Research · Healthcare
Exchange
NASDAQ
Winston Score
29
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 23, 2026 · filings through Jun 30, 2026
How the score breaks down
Quality
Weak
Growth
Good
Cash Flow
Weak
Stability
Good
Valuation
Data not available

Winston Score History

The full picture

Twist Bioscience makes synthetic DNA — strands of genetic code built from scratch in a lab. Scientists, pharmaceutical companies, and agricultural researchers buy this DNA to develop new medicines, study diseases, and engineer crops. Twist is known for its silicon-based DNA synthesis platform, which lets it produce DNA faster and more cheaply than older methods.

The company sells its synthetic DNA products directly to research labs, biotech firms, and government agencies, primarily in North America and Europe. With a gross margin around 52%, Twist earns money on each DNA order, but it still spends heavily on research and operations, resulting in significant losses. Its core competitive advantage is its proprietary manufacturing technology, which allows it to pack far more DNA synthesis reactions onto a chip than traditional methods. The main risk is that Twist must keep growing revenue fast enough to eventually cover its operating costs, and competition from other DNA synthesis companies could pressure pricing over time.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+23.2% YoY

YoY Growth Rate

Steady revenue growth

EPS Growth

-264.7% YoY

YoY Growth Rate

Earnings declining

Insider Activity

4.1%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~2 years

$235M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

$235M cash & investments at current burn rate

Growth context

Twist Bioscience Corporation is growing revenue at 23% year-over-year. The Winston Score measures business quality today — these growth metrics show what could matter tomorrow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Profit per sale
Gross Margin
52.8%
Healthy — 52.8% gross margin
Profit after running costs
Operating Margin
-30.6%
Losing money on operations — -30.6%
Return on the money invested
ROCE
-26.9%
Weak — -26.9% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
+19.2%
Fast-growing sales (+19.2% YoY)
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
6/8 quarters
Earnings grew in most of the last 8 quarters

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
-22.0%
Burning cash (-22.0%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

What it owes vs what it owns
Debt / Equity
0.21
Conservative — low debt load (0.21)
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
no trend
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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