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Tyra Biosciences

TYRA
Biotechnology · Healthcare
Price
$26.05
+0.36 (+1.40%)
Market Cap
$1.55B
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+43.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 41.4M (2021) → 59.6M (2025)

Winston Score History

The full picture

Tyra Biosciences is a clinical-stage biotechnology company focused on developing drugs to treat genetic diseases caused by mutations in a protein called FGFR, which stands for fibroblast growth factor receptor. These mutations can cause conditions like achondroplasia, a form of dwarfism, as well as certain cancers. The company's main customers are patients with these rare genetic conditions, and it works within the rare disease and oncology drug development space.

Tyra does not yet sell any approved products, so it currently earns no revenue — it funds its operations through cash raised from investors. The company is based in the United States and is running clinical trials to test its lead drug candidates, including TYRA-300 for achondroplasia. Its competitive position depends on whether its drugs prove safer or more effective than existing treatments, such as BioMarin's Voxzogo. The biggest risk is clinical failure, since most experimental drugs do not make it through trials to FDA approval.

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

-46.8% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$103M/ year

Rising (+29% vs prior year)

R&D investment increasing — building for the future

Insider Activity

25.7%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

~3 years

$354M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$354M cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Profit per sale
Gross Margin
N/A
Data not available
Profit after running costs
Operating Margin
N/A
Data not available
Return on the money invested
ROCE
-45.4%
Weak — -45.4% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales growth
Sales YoY
N/A
Data not available
Profit growth
EPS YoY
N/A
Data not available
How steady the profit is
EPS Consistency
2/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Profit that turns into cash
Cash Conversion
N/A
Data not available
Spare cash per sale
FCF Margin
N/A
Data not available

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Stability

What it owes vs what it owns
Debt / Equity
N/A
Data not available
Covers its interest
Interest Cover
N/A
Data not available

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Valuation

Price vs profit
P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
Cheaper or dearer next year
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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